Evaxion reports three-year data from the phase 2 trial of its personalized cancer vaccine EVX-01 in patients with advanced melanoma: the vaccine induced an immune response in all patients, with 89% of vaccine neoantigens generating specific T-cell responses. In the third year, when EVX-01 was given as monotherapy, T-cell responses were sustained and all patients kept the clinical response seen at two years, with no tumor progression. The data will be presented as a poster at the ESMO 2026 Congress in Madrid on October 24, followed by a webinar on October 29. At two years, 92% of patients were still responding with no relapses, and the neoantigen hit rate of 86% rose to 89% after analysis of samples from the one-year extension phase.
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Original headline: Evaxion announces 89 % vaccine target precision and sustained T - cell and clinical responses at three - year follow - up in phase 2 trial with personalized cancer vaccine EVX - 01
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