MSFT: price today and chart

Syndax said its MAXPIRe Phase 2 trial of axatilimab in idiopathic pulmonary fibrosis failed to meet its primary endpoint of slowing lung function decline, so it will halt further IPF development for the drug while other trials continue. Safety in IPF was comparable to placebo, and ongoing studies and the approved chronic GVHD use of Niktimvo are unaffected. The article views the setback as a narrowing of axatilimab's opportunity rather than a franchise-level issue, with Revuforj and Niktimvo still the core commercial pillars. However, Syndax remains loss-making and spends roughly US$400 million a year on R&D and SG&A, so revenue growth is the key factor to watch.

GFI Software has built its Eloquens AI assistant directly into GFI KerioConnect, the mail and collaboration server used by more than 30,000 organizations, announced in Prague on October 13, 2026. The feature targets organizations that run their own mail to control data, meet regulations or keep costs down, rather than moving to cloud services such as Microsoft 365 Copilot or Gmail’s Gemini. Eloquens AI sorts incoming messages within minutes: newsletters and notifications go to a “No Reply Needed” folder, decisions stay labeled in the inbox, and routine questions receive draft replies in the user’s own voice, each with its reasoning. It stays off until an administrator enables it, keeps mail on the customer’s own server, can be applied to selected mailboxes and turned off at any time, and offers a 30-day free trial with one click, which managed service providers can also offer to their customers.

Microsoft has announced Maia 300, its third-generation in-house AI chip, and plans to ramp up Maia from 2027 as the primary inference system for its own products. Microsoft estimates Maia 300 will generate 40% more tokens per megawatt than top GPU-based systems, though this is its own projection, and it still plans to deploy Nvidia's next-generation Vera Rubin systems. Nvidia's fiscal Q2 2027 revenue reached $96.2 billion, up 106% year over year, while spending by hyperscale customers more than doubled to $48.7 billion. The author argues that custom chips like Maia may take some work from Nvidia, but the stock, about 6% below its October 6 record close, does not appear priced as if Nvidia will keep all of it. It trades at roughly 14 times the average analyst earnings estimate for fiscal 2028, compared with about 23 times for Microsoft's fiscal 2028.

Palo Alto Networks (PANW) shares fell 4.7% in the afternoon session after Phillip Securities downgraded the stock to Neutral from Buy with a $346 price target, about 17% below the previous close of $418.78. Analyst Alif Fahmi called the shares stretched at 97 times earnings versus a historical average of 54 times, while keeping an 'overweight' view on software and naming Microsoft, Oracle, Palantir and Snowflake as preferred names. The stock had gained 5.1% in the prior session and more than 120% in 2026 so far. The article links the drop to profit-taking after the year-to-date rally, with shares closing at $403.81, down 3.6%.

Microsoft has sued brokerage JLL in New York County Supreme Court, seeking coverage for legal costs tied to a 2023 forklift accident during the build-out of its 150K SF office at 122 Fifth Ave. According to the complaint, JLL, the project manager, agreed to add Microsoft to its $10M liability insurance but did not, and refused to cover Microsoft after construction worker Anyello Frayind sued over permanent injuries from the forklift. JLL argued that the forklift operator's employer and Frayind were working on a separate project inside the building, but Microsoft says that claim is “factually incorrect, was made without investigation and was not in good faith.” The building is owned by The Bromley Cos., which redeveloped it at a cost of $100M in conjunction with Microsoft's arrival, according to the New York Post.